Maximillian Gabriel Marin
About me
I am postdoctoral research fellow in the Li Lab at Dana-Farber Cancer Institute and Harvard Medical School. I completed my PhD studying the evolution of Mycobacterium tuberculosis in the Farhat Lab at Harvard Medical School.
Publications
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M. Marin, C. Wippel, N. Quinones-Olvera, M. Behruznia, B.M. Jeffrey, M. Harris, B.C. Mann, A. Rosenthal, K.R. Jacobson, R.M. Warren, H. Li, C.J. Meehan, & M.R. Farhat. Analysis of the limited M. tuberculosis accessory genome reveals potential pitfalls of pan-genome analysis approaches. Bioinformatics (2025)
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M. Marin, M.R. Chase, N. Quinones-Olvera, S. Wakabayashi, D. Mugahid, S.M. Fortune, M.R. Farhat, & M.C. Chao. Complete genome sequence of a virulent barcoded Mycobacterium tuberculosis strain Erdman commonly used for non-human primate infection studies. Microbiology Resource Announcements (2025)
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Y. Ektefaie, A. Shen, D. Bykova, M. Marin, M. Zitnik, & M. Farhat. Evaluating generalizability of artificial intelligence models for molecular datasets. Nature Machine Intelligence (2024)
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H. Li, M. Marin, & M.R. Farhat. Exploring gene content with pangenome gene graphs. Bioinformatics (2024)
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N. Quinones-Olvera, S.V. Owen, L.M. McCully, M. Marin, E.A. Rand, A.C. Fan, O.J. Martins Dosumu, K. Paul, C.E. Sanchez Castaño, R. Petherbridge, J.S. Paull, M. Baym. Diverse and abundant phages exploit conjugative plasmids. Nature Communications (2024)
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M. Marin, R. Vargas, M. Harris, B. Jeffrey, L.E. Epperson, D. Durbin, M. Strong, M. Salfinger, Z. Iqbal, I. Akhundova, S. Vashakidze, V. Crudu, A. Rosenthal, & M.R. Farhat. Benchmarking the empirical accuracy of short-read sequencing across the M. tuberculosis genome. Bioinformatics (2022)
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C.M. Soulette, E. Hrabeta-Robinson, A. Tang, M. Marin, A.N. Brooks. Nanopore sequencing reveals U2AF1 S34F-associated full-length isoforms. Life Science Alliance (2023)
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R. Vargas, L. Freschi, M. Marin, L.E. Epperson, M. Smith, I. Oussenko, D. Durbin, M. Strong, M. Salfinger, & M.R. Farhat. In-host population dynamics of Mycobacterium tuberculosis complex during active disease. eLife (2021)
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M. Gröschel, M. Owens, L. Freschi, R. Vargas, M. Marin, J. Phelan, Z. Iqbal, A. Dixit, & M.R. Farhat. GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning. Genome Medicine (2021)
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C.E. Trujillo et al. (Including M. Marin) Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment. Science (2021)
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The Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium (Including M. Marin) Genomic basis for RNA alterations in cancer. Nature (2020)
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G. Bhagavatula, M.S. Rich, D.L. Young, M. Marin, & S. Fields. A Massively Parallel Fluorescence Assay to Characterize the Effects of Synonymous Mutations on TP53 Expression. Molecular Cancer Research (2017)
Education
Ph.D. in Systems, Synthetic, & Quantitative Biology 2017–2023 Harvard University, Graduate School of Arts and Sciences Advisor: Maha Farhat Thesis: Peering into the “dark matter” of the M. tuberculosis genome using long-read sequencing
B.S. in Molecular, Cellular, & Developmental Biology 2013–2017 University of California, Santa Cruz — Summa cum laude Advisor: Angela Brooks Thesis: Designing a high-throughput functional screen of skipped exons contributing to lung cancer development
Honors & Awards
- NLM Biomedical Informatics and Data Science Postdoctoral Fellowship 2023–2025
- Deans’ Award for Senior Thesis, Engineering Division — UCSC 2017
- Howard Hughes Medical Institute Exceptional Research Opportunities Program 2016
- Koret Undergraduate Research Scholarship 2016–2017
- Initiative for Maximizing Student Development (IMSD) Scholar 2015–2017
- The C. Fiore Prize in Organic Chemistry — UC Santa Cruz 2016
- Broad Institute Summer Research Program in Genomics 2015